Dec 01, 2010 · In order to prove this effect, TEG samples from a patient on heparin therapy were run in parallel with 2 different antiheparin reagents: protamine 10 mg/mL diluted to a concentration of 0.033 mg/mL and Dade Hepzyme (Siemens, Deerfield, Illinois). Hepzyme is an enzyme that cleaves heparin molecules and is able to remove up to 2 IU/mL of heparin ...